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KMID : 0191120080230020256
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Journal of Korean Medical Science
2008 Volume.23 No. 2 p.256 ~ p.261
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Visceral Fat Thickness Predicts Fatty Liver in Koreans with Type 2 Diabetes Mellitus
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Kim Hai-Jin
Cha Bong-Soo
Ahn Chul-Woo
Kim Kyung-Rae
Lim Sung-Kil
Lee Hyun-Chul
Nam Ji-Sun
Kang Eun-Seok
Lee Eun-Jig
Huh Kap-Bum
Cho Min-Ho
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Abstract
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Our aim was to study whether visceral adiposity is a predictor of diabetic fatty liver in Korean type 2 diabetes mellitus. In this study, abdominal ultrasonography was used to assess the presence of fatty liver in 1,898 patients with type 2 diabetes. We measured visceral fat thickness by high-resolutional ultrasonography and insulin resistance by Kitt. Half of the cohort had a fatty liver (50.2%). High visceral fat thickness had the highest odds ratio for developing fatty liver in both sexes (odds ratio [S.D]: 3.14 [2.24-4.69], p<0.00 in male, 2.84 [2.04-3.93], p<0.00 in female). In addition, visceral fat thickness of 42.45 and 37.7 mm in men and women, respectively, were chosen as the discriminating value to predict the presence of fatty liver with a sensitivity of 71% and 73% and a specificity of 70% and 70% in men and women, respectively. The area under the receiver-operating characteristics curve was 0.759 in men and 0.764 in women. Therefore we could conclude that the degree of visceral adiposity predicts the presence of fatty liver type 2 diabetes mellitus, whether centrally obese or not, suggesting that hepatic fat accumulation in a diabetic fatty liver may be influenced by visceral fat accumulation regardless of waist circumference.
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KEYWORD
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Visceral Fat Thickness, Fatty Liver, Type 2 Diabetes Mellitus
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